4EVY
Crystal structure of aminoglycoside antibiotic 6'-N-acetyltransferase AAC(6')-Ig from Acinetobacter haemolyticus in complex with tobramycin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Aminoglycoside N(6')-acetyltransferase type 1 | polymer | 166 | 18899.3 | 2 | UniProt (Q44057) Pfam (PF00583) In PDB | Acinetobacter haemolyticus | AAC(6')-Ig, Aminoglycoside resistance protein |
2 | A, B | TOBRAMYCIN | non-polymer | 467.5 | 2 | Chemie (TOY) | |||
3 | A, B | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
4 | A, B | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
5 | water | water | 18.0 | 223 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 145 (UniProt: Q44057)
PDB | External Database | Details |
---|---|---|
Met -20 | - | expression tag |
Gly -19 | - | expression tag |
Ser -18 | - | expression tag |
Ser -17 | - | expression tag |
His -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
Ser -10 | - | expression tag |
Ser -9 | - | expression tag |
Gly -8 | - | expression tag |
Arg -7 | - | expression tag |
Glu -6 | - | expression tag |
Asn -5 | - | expression tag |
Leu -4 | - | expression tag |
Tyr -3 | - | expression tag |
Phe -2 | - | expression tag |
Gln -1 | - | expression tag |
Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 37798.6 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 1119.6 | |
All* | Total formula weight | 38918.2 |