4EVY
Crystal structure of aminoglycoside antibiotic 6'-N-acetyltransferase AAC(6')-Ig from Acinetobacter haemolyticus in complex with tobramycin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Aminoglycoside N(6')-acetyltransferase type 1 | polymer | 166 | 18899.3 | 2 | UniProt (Q44057) | Acinetobacter haemolyticus | AAC(6')-Ig, Aminoglycoside resistance protein |
| 2 | C, G (A, B) | TOBRAMYCIN | non-polymer | 467.5 | 2 | Chemie (TOY) PubChem (16220018) PubChem (16394558) PubChem (16758168) PubChem (20849286) PubChem (5496) PubChem (176612034) PubChem (16398934) PubChem (44120121) PubChem (44176766) PubChem (44452837) PubChem (24014406) PubChem (44120122) PubChem (58097828) PubChem (67891005) PubChem (68150709) PubChem (70799053) PubChem (70809331) PubChem (68151045) PubChem (71306742) PubChem (71752596) PubChem (73265187) PubChem (36294) PubChem (6604388) PubChem (92328112) PubChem (92328113) PubChem (92328114) PubChem (92331686) PubChem (92331687) PubChem (92331688) PubChem (11340303) PubChem (90470031) PubChem (95858849) PubChem (98114453) PubChem (98114456) PubChem (92045464) PubChem (92328115) PubChem (92331689) PubChem (94865134) PubChem (95858846) PubChem (95858847) PubChem (118421979) PubChem (124715005) PubChem (124715004) PubChem (124715007) PubChem (124746729) PubChem (9804613) PubChem (9934285) PubChem (131839603) PubChem (118912247) PubChem (121277573) PubChem (121343178) PubChem (122581308) PubChem (123134053) PubChem (124715006) PubChem (124746730) PubChem (125462943) PubChem (125462944) PubChem (125462945) PubChem (125462946) PubChem (129009857) PubChem (129660520) PubChem (131632463) PubChem (132286112) PubChem (140820779) PubChem (141657335) PubChem (145081758) PubChem (145746421) PubChem (155070252) PubChem (162893911) PubChem (167525425) PubChem (169006915) PubChem (170547748) PubChem (170999940) PubChem (171669583) PubChem (173721899) PubChem (173745810) | |||
| 3 | D, H (A, B) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) PubChem (813) | |||
| 4 | E, F, I (A, B) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) PubChem (312) | |||
| 5 | J, K (A, B) | water | water | 18.0 | 223 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 145 (UniProt: Q44057)
| PDB | External Database | Details |
|---|---|---|
| Met -20 | - | expression tag |
| Gly -19 | - | expression tag |
| Ser -18 | - | expression tag |
| Ser -17 | - | expression tag |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| Ser -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Gly -8 | - | expression tag |
| Arg -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Asn -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Tyr -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Gln -1 | - | expression tag |
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37798.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1119.6 | |
| All* | Total formula weight | 38918.2 |
