4ERP
Crystal structure of a gemcitabine-diphosphate inhibited E. coli class Ia ribonucleotide reductase complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Ribonucleoside-diphosphate reductase 1 subunit alpha | polymer | 761 | 85877.1 | 4 | UniProt (P00452) Pfam (PF03477) Pfam (PF00317) Pfam (PF02867) | Escherichia coli K-12 | Protein B1, Ribonucleoside-diphosphate reductase 1 R1 subunit, Ribonucleotide reductase 1 |
| 2 | E, F, G, H (E, F, G, H) | Ribonucleoside-diphosphate reductase 1 subunit beta | polymer | 375 | 43426.9 | 4 | UniProt (P69924) Pfam (PF00268) | Escherichia coli K-12 | Protein B2, Protein R2, Ribonucleotide reductase 1 |
| 3 | I, J, K, L (A, B, C, D) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 4 | Chemie (ATP) | |||
| 4 | M, N, O, P (E, F, G, H) | MU-OXO-DIIRON | non-polymer | 127.7 | 4 | Chemie (FEO) | |||
| 5 | Q, R, S, T (E, F, G, H) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 517215.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2539.5 | |
| All* | Total formula weight | 519755.3 |
