4ELL
Structure of the inactive retinoblastoma protein pocket domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Retinoblastoma-associated protein | polymer | 411 | 47675.0 | 2 | UniProt (P06400) Pfam (PF01858) Pfam (PF01857) In PDB | Homo sapiens (human) | p105-Rb, pRb, Rb, pp110 |
| 2 | water | water | 18.0 | 355 | Chemie (HOH) |
Sequence modifications
A, B: 380 - 787 (UniProt: P06400)
| PDB | External Database | Details |
|---|---|---|
| Gly 377 | - | expression tag |
| Glu 378 | - | expression tag |
| Phe 379 | - | expression tag |
| Phe 561 | Leu 561 | engineered mutation |
| Glu 608 | Ser 608 | engineered mutation |
| Ala 612 | Ser 612 | conflict |
| Ala 780 | Ser 780 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 95350.0 | |
| All* | Total formula weight | 95350.0 |
