4EJH
Human Cytochrome P450 2A13 in complex with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Cytochrome P450 2A13 | polymer | 476 | 54804.8 | 8 | UniProt (Q16696) Pfam (PF00067) | Homo sapiens (human) | CYPIIA13 |
| 2 | I, K, M, O, Q... (A, B, C, D, E...) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 8 | Chemie (HEM) | |||
| 3 | J, L, N, P, R... (A, B, C, D, E...) | 4-[methyl(nitroso)amino]-1-(pyridin-3-yl)butan-1-one | non-polymer | 207.2 | 6 | Chemie (0QA) | |||
| 4 | V, X (G, H) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | AA, BA, CA, DA, EA... (C, D, E, F, G...) | water | water | 18.0 | 261 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 31 - 494 (UniProt: Q16696)
| PDB | External Database | Details |
|---|---|---|
| Met 23 | - | initiating methionine |
| Ala 24 | - | expression tag |
| Lys 25 | - | expression tag |
| Lys 26 | - | expression tag |
| Thr 27 | - | expression tag |
| Ser 28 | - | expression tag |
| Ser 29 | - | expression tag |
| Lys 30 | - | expression tag |
| His 495 | - | expression tag |
| His 496 | - | expression tag |
| His 497 | - | expression tag |
| His 498 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 438438.1 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 6359.5 | |
| All* | Total formula weight | 444797.5 |
