4EIN
Crystal structure of mouse thymidylate synthase in binary complex with a substrate analogue and strong inhibitor, N(4)-hydroxy-2'-deoxycytidine-5'-monophosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Thymidylate synthase | polymer | 307 | 35001.0 | 2 | UniProt (P07607) Pfam (PF00303) In PDB | Mus musculus (mouse) | TS, TSase |
| 2 | A, B | 2'-deoxy-N-hydroxycytidine 5'-(dihydrogen phosphate) | non-polymer | 323.2 | 2 | Chemie (NOH) | |||
| 3 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | water | water | 18.0 | 741 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 70002.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 738.5 | |
| All* | Total formula weight | 70740.5 |
