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4EIK

Crystal Structure of the Human Fyn SH3 domain in complex with the synthetic peptide VSL12

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tyrosine-protein kinase Fynpolymer647171.81UniProt (P06241)
Pfam (PF00018)
Homo sapiensProto-oncogene Syn, Proto-oncogene c-Fyn, Src-like kinase, SLK, p59-Fyn
2B
(B)
VSL12 peptidepolymer121317.61synthetic construct
3C
(A)
SODIUM IONnon-polymer23.01Chemie (NA)
4D, E
(A, B)
waterwater18.040Chemie (HOH)
Sequence modifications
A: 81 - 143 (UniProt: P06241)
PDBExternal DatabaseDetails
Met 80-initiating methionine
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight8489.4
Non-Polymers*Number of molecules1
Total formula weight23.0
All*Total formula weight8512.4
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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