4EHI

An X-ray Crystal Structure of a putative Bifunctional Phosphoribosylaminoimidazolecarboxamide Formyltransferase/IMP Cyclohydrolase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Bifunctional purine biosynthesis protein PurH	polymer	534	59875.8	2	UniProt (Q9PNY2) Pfam (PF02142) Pfam (PF01808) In PDB	Campylobacter jejuni subsp. jejuni	Phosphoribosylaminoimidazolecarboxamide formyltransferase, AICAR transformylase, IMP cyclohydrolase, ATIC, IMP synthase, Inosinicase
2	A	2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		209.2	1	Chemie (BTB)
3	A, B	SULFATE ION	non-polymer		96.1	9	Chemie (SO4)
4		water	water		18.0	554	Chemie (HOH)

Sequence modifications

A, B: 1 - 510 (UniProt: Q9PNY2)

PDB	External Database	Details
Mse -23	-	EXPRESSION TAG
His -22	-	EXPRESSION TAG
His -21	-	EXPRESSION TAG
His -20	-	EXPRESSION TAG
His -19	-	EXPRESSION TAG
His -18	-	EXPRESSION TAG
His -17	-	EXPRESSION TAG
Ser -16	-	EXPRESSION TAG
Ser -15	-	EXPRESSION TAG
Gly -14	-	EXPRESSION TAG
Val -13	-	EXPRESSION TAG
Asp -12	-	EXPRESSION TAG
Leu -11	-	EXPRESSION TAG
Gly -10	-	EXPRESSION TAG
Thr -9	-	EXPRESSION TAG
Glu -8	-	EXPRESSION TAG
Asn -7	-	EXPRESSION TAG
Leu -6	-	EXPRESSION TAG
Tyr -5	-	EXPRESSION TAG
Phe -4	-	EXPRESSION TAG
Gln -3	-	EXPRESSION TAG
Ser -2	-	EXPRESSION TAG
Asn -1	-	EXPRESSION TAG
Ala 0	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	119751.6
Non-Polymers*	Number of molecules	10
	Total formula weight	1073.8
All*	Total formula weight	120825.4

*Water molecules are not included.