4EHI

An X-ray Crystal Structure of a putative Bifunctional Phosphoribosylaminoimidazolecarboxamide Formyltransferase/IMP Cyclohydrolase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Bifunctional purine biosynthesis protein PurH	polymer	534	59875.8	2	UniProt (Q9PNY2) Pfam (PF02142) Pfam (PF01808)	Campylobacter jejuni subsp. jejuni	Phosphoribosylaminoimidazolecarboxamide formyltransferase, AICAR transformylase, IMP cyclohydrolase, ATIC, IMP synthase, Inosinicase
2	C (A)	2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		209.2	1	Chemie (BTB)
3	D, E, F, G, H... (A, B)	SULFATE ION	non-polymer		96.1	9	Chemie (SO4)
4	M, N (A, B)	water	water		18.0	554	Chemie (HOH)

Sequence modifications

A, B: 1 - 510 (UniProt: Q9PNY2)

PDB	External Database	Details
Mse -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
Gly -14	-	expression tag
Val -13	-	expression tag
Asp -12	-	expression tag
Leu -11	-	expression tag
Gly -10	-	expression tag
Thr -9	-	expression tag
Glu -8	-	expression tag
Asn -7	-	expression tag
Leu -6	-	expression tag
Tyr -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	119751.6
Non-Polymers*	Number of molecules	10
	Total formula weight	1073.8
All*	Total formula weight	120825.4

*Water molecules are not included.