4EFK
Pantothenate synthetase in complex with N,N-DIMETHYLTHIOPHENE-3-SULFONAMIDE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Pantothenate synthetase | polymer | 300 | 31500.1 | 2 | UniProt (P0A5R0) Pfam (PF02569) UniProt (by SIFTS) (P9WIL5) | Mycobacterium tuberculosis | PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme |
| 2 | C, D, J (A, B) | N,N-dimethylthiophene-3-sulfonamide | non-polymer | 191.3 | 3 | Chemie (0OC) | |||
| 3 | E, K, M (A, B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | F, G, I, N, O... (A, B) | ETHANOL | non-polymer | 46.1 | 7 | Chemie (EOH) | |||
| 5 | H (A) | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 6 | L (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 7 | R, S (A, B) | water | water | 18.0 | 391 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 300 (UniProt: P0A5R0)
| PDB | External Database | Details |
|---|---|---|
| Ala 2 | Thr 2 | engineered mutation |
| Gly 77 | Glu 77 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63000.2 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1337.7 | |
| All* | Total formula weight | 64337.9 |
