4EF6
Crystal Structure of Mycobacterium tuberculosis Pantothenate synthetase in complex with fragment 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Pantothenate synthetase | polymer | 300 | 31500.1 | 2 | UniProt (P0A5R0) Pfam (PF02569) UniProt (by SIFTS) (P9WIL5) | Mycobacterium tuberculosis | PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme |
| 2 | C, D, E, J, K (A) | ETHANOL | non-polymer | 46.1 | 5 | Chemie (EOH) | |||
| 3 | F, Q (A, B) | 3-(1,3-benzodioxol-5-yl)propanoic acid | non-polymer | 194.2 | 2 | Chemie (I2E) | |||
| 4 | G, H, L (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 5 | I, M, N, O, P (A, B) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 6 | R, S (A, B) | water | water | 18.0 | 489 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 300 (UniProt: P0A5R0)
| PDB | External Database | Details |
|---|---|---|
| Ala 2 | Thr 2 | engineered mutation |
| Gly 77 | Glu 77 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63000.2 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1265.4 | |
| All* | Total formula weight | 64265.6 |
