4EDH
The crystal structure of thymidylate kinase from Pseudomonas aeruginosa PAO1 in complex with ADP,TMP and Mg.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Thymidylate kinase | polymer | 213 | 23408.6 | 2 | UniProt (Q9HZN8) Pfam (PF02223) | Pseudomonas aeruginosa PAO1 | dTMP kinase |
| 2 | C, H (A, B) | THYMIDINE-5'-PHOSPHATE | non-polymer | 322.2 | 2 | Chemie (TMP) | |||
| 3 | D, I (A, B) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 4 | E, J (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | F (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 6 | G (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 7 | K (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 8 | L, M (A, B) | water | water | 18.0 | 453 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 210 (UniProt: Q9HZN8)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 46817.2 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1827.7 | |
| All* | Total formula weight | 48644.9 |
