4EDH
The crystal structure of thymidylate kinase from Pseudomonas aeruginosa PAO1 in complex with ADP,TMP and Mg.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Thymidylate kinase | polymer | 213 | 23408.6 | 2 | UniProt (Q9HZN8) Pfam (PF02223) | Pseudomonas aeruginosa PAO1 | dTMP kinase |
| 2 | C, H (A, B) | THYMIDINE-5'-PHOSPHATE | non-polymer | 322.2 | 2 | Chemie (TMP) PubChem (18531120) PubChem (20711568) PubChem (1139) PubChem (23657880) PubChem (24802545) PubChem (444919) PubChem (44361457) PubChem (25113134) PubChem (51397487) PubChem (5748250) PubChem (9700) PubChem (10147784) PubChem (5274091) PubChem (129069890) PubChem (133126478) PubChem (164603144) | |||
| 3 | D, I (A, B) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 4 | E, J (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 5 | F (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) PubChem (3777159) | |||
| 6 | G (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 7 | K (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 8 | L, M (A, B) | water | water | 18.0 | 453 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 210 (UniProt: Q9HZN8)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 46817.2 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1827.7 | |
| All* | Total formula weight | 48644.9 |
