4ECK
Crystal Structure of the Toxoplasma gondii TS-DHFR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bifunctional dihydrofolate reductase-thymidylate synthase | polymer | 610 | 68842.7 | 2 | UniProt (Q07422) Pfam (PF00186) Pfam (PF00303) | Toxoplasma gondii | DHFR-TS, Dihydrofolate reductase, Thymidylate synthase |
| 2 | C, G (A, B) | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE | non-polymer | 308.2 | 2 | Chemie (UMP) | |||
| 3 | D, H (A, B) | 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID | non-polymer | 477.5 | 2 | Chemie (CB3) | |||
| 4 | E, I (A, B) | FOLIC ACID | non-polymer | 441.4 | 2 | Chemie (FOL) | |||
| 5 | F, J (A, B) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 137685.3 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 3944.9 | |
| All* | Total formula weight | 141630.3 |
