4EBK
Crystal structure of aminoglycoside 4'-O-adenylyltransferase ANT(4')-IIb, tobramycin-bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Aminoglycoside nucleotidyltransferase | polymer | 272 | 30824.6 | 2 | UniProt (Q83V96) UniProt (by SIFTS) (D0E7M2) | Pseudomonas aeruginosa | |
| 2 | C, W (A, B) | TOBRAMYCIN | non-polymer | 467.5 | 2 | Chemie (TOY) PubChem (16220018) PubChem (16394558) PubChem (16758168) PubChem (20849286) PubChem (5496) PubChem (176612034) PubChem (16398934) PubChem (44120121) PubChem (44176766) PubChem (44452837) PubChem (24014406) PubChem (44120122) PubChem (58097828) PubChem (67891005) PubChem (68150709) PubChem (70799053) PubChem (70809331) PubChem (68151045) PubChem (71306742) PubChem (71752596) PubChem (73265187) PubChem (36294) PubChem (6604388) PubChem (92328112) PubChem (92328113) PubChem (92328114) PubChem (92331686) PubChem (92331687) PubChem (92331688) PubChem (11340303) PubChem (90470031) PubChem (95858849) PubChem (98114453) PubChem (98114456) PubChem (92045464) PubChem (92328115) PubChem (92331689) PubChem (94865134) PubChem (95858846) PubChem (95858847) PubChem (118421979) PubChem (124715005) PubChem (124715004) PubChem (124715007) PubChem (124746729) PubChem (9804613) PubChem (9934285) PubChem (131839603) PubChem (118912247) PubChem (121277573) PubChem (121343178) PubChem (122581308) PubChem (123134053) PubChem (124715006) PubChem (124746730) PubChem (125462943) PubChem (125462944) PubChem (125462945) PubChem (125462946) PubChem (129009857) PubChem (129660520) PubChem (131632463) PubChem (132286112) PubChem (140820779) PubChem (141657335) PubChem (145081758) PubChem (145746421) PubChem (155070252) PubChem (162893911) PubChem (167525425) PubChem (169006915) PubChem (170547748) PubChem (170999940) PubChem (171669583) PubChem (173721899) PubChem (173745810) | |||
| 3 | D, X (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | AA, BA, CA, DA, E... (B, A) | IODIDE ION | non-polymer | 126.9 | 12 | Chemie (IOD) PubChem (30165) | |||
| 5 | EA, FA, GA, HA, IA... (B, A) | CHLORIDE ION | non-polymer | 35.5 | 17 | Chemie (CL) PubChem (312) | |||
| 6 | JA, KA (A, B) | water | water | 18.0 | 475 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 251 (UniProt: Q83V96)
| PDB | External Database | Details |
|---|---|---|
| Mse -20 | - | initiating methionine |
| Gly -19 | - | expression tag |
| Ser -18 | - | expression tag |
| Ser -17 | - | expression tag |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| Ser -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Gly -8 | - | expression tag |
| Arg -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Asn -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Tyr -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Gln -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Val 1 | - | expression tag |
| Leu 111 | Met 111 | SEE REMARK 999 |
| Asp 127 | Asn 127 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 61649.2 | |
| Non-Polymers* | Number of molecules | 33 |
| Total formula weight | 3184.7 | |
| All* | Total formula weight | 64833.9 |
