4E9D
The structure of the polo-box domain (PBD) of polo-like kinase 1 (Plk1) in complex with 3-(1-benzothiophen-2-yl)propanoyl-derivatized DPPLHSpTA peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase PLK1 | polymer | 232 | 26755.5 | 1 | UniProt (P53350) Pfam (PF00659) | Homo sapiens (human) | Polo-like kinase 1, PLK-1, Serine/threonine-protein kinase 13, STPK13 |
| 2 | B (E) | 3-(1-benzothiophen-2-yl)propanoyl-derivatized DPPLHSpTA peptide | polymer | 10 | 1104.1 | 1 | BIRD (PRD_000810) | ||
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D, E (A, E) | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence modifications
A: 371 - 594 (UniProt: P53350)
| PDB | External Database | Details |
|---|---|---|
| Gly 363 | - | expression tag |
| Pro 364 | - | expression tag |
| Leu 365 | - | expression tag |
| Gly 366 | - | expression tag |
| Ser 367 | - | expression tag |
| Pro 368 | - | expression tag |
| Glu 369 | - | expression tag |
| Phe 370 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27859.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 27951.7 |
