4E93
Crystal structure of human Feline Sarcoma Viral Oncogene Homologue (v-FES)in complex with TAE684
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Tyrosine-protein kinase Fes/Fps | polymer | 377 | 42758.0 | 1 | UniProt (P07332) Pfam (PF00017) Pfam (PF07714) In PDB | Homo sapiens (human) | Feline sarcoma/Fujinami avian sarcoma oncogene homolog, Proto-oncogene c-Fes, Proto-oncogene c-Fps, p93c-fes |
2 | A | 5-CHLORO-N-[2-METHOXY-4-[4-(4-METHYLPIPERAZIN-1-YL)PIPERIDIN-1-YL]PHENYL]-N'-(2-PROPAN-2-YLSULFONYLPHENYL)PYRIMIDINE-2,4-DIAMINE | non-polymer | 614.2 | 1 | Chemie (GUI) | |||
3 | water | water | 18.0 | 258 | Chemie (HOH) |
Sequence modifications
A: 448 - 822 (UniProt: P07332)
PDB | External Database | Details |
---|---|---|
Ser 446 | - | expression tag |
Met 447 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 42758.0 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 614.2 | |
All* | Total formula weight | 43372.2 |