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4E5Y

Structure of human FX protein, the key enzyme in the biosynthesis of GDP-L-fucose

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
GDP-L-fucose synthasepolymer32135935.64UniProt (Q13630)
Pfam (PF01370)
Homo sapiens (human)GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase, Protein FX, Red cell NADP(H)-binding protein, Short-chain dehydrogenase/reductase family 4E member 1
2E, F, G, H
(A, B, C, D)
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer745.44Chemie (NDP)
3I, J, K, L
(A, B, C, D)
waterwater18.022Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight143742.4
Non-Polymers*Number of molecules4
Total formula weight2981.7
All*Total formula weight146724.0
*Water molecules are not included.

242842

PDB entries from 2025-10-08

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