4E4L
JAK1 kinase (JH1 domain) in complex with compound 30
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, E, D) | Tyrosine-protein kinase JAK1 | polymer | 302 | 34746.6 | 4 | UniProt (P23458) Pfam (PF07714) | Homo sapiens (human) | Janus kinase 1, JAK-1 |
| 2 | E, F, G, H (A, B, D) | 1-[4-methyl-1-(methylsulfonyl)piperidin-4-yl]-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine | non-polymer | 333.4 | 4 | Chemie (0NH) | |||
| 3 | I, J, K, L (A, B, E, D) | water | water | 18.0 | 552 | Chemie (HOH) |
Sequence modifications
A, B, E, D: 854 - 1154 (UniProt: P23458)
| PDB | External Database | Details |
|---|---|---|
| Gly 853 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 138986.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1333.6 | |
| All* | Total formula weight | 140320.0 |
