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4E4H

Crystal structure of Histone Demethylase NO66

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Lysine-specific demethylase NO66polymer46352657.54UniProt (Q9H6W3)
Pfam (PF08007)
Pfam (PF21233)
Homo sapiens (human)Nucleolar protein 66, hsNO66
2E, G, H, K
(A, B, C, D)
FE (III) IONnon-polymer55.84Chemie (FE)
3F
(A)
ACETATE IONnon-polymer59.01Chemie (ACT)
4I
(C)
GLYCEROLnon-polymer92.11Chemie (GOL)
5J
(C)
DI(HYDROXYETHYL)ETHERnon-polymer106.11Chemie (PEG)
6L, M, N, O
(A, B, C, D)
waterwater18.0589Chemie (HOH)
Sequence modifications
A, B, C, D: 183 - 641 (UniProt: Q9H6W3)
PDBExternal DatabaseDetails
His 179-expression tag
Met 180-expression tag
Gly 181-expression tag
Ser 182-expression tag
Ala 364Val 364SEE REMARK 999
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight210630.2
Non-Polymers*Number of molecules7
Total formula weight480.6
All*Total formula weight211110.8
*Water molecules are not included.

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PDB entries from 2025-06-18

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