4E36
Crystal structure of the human Endoplasmic Reticulum Aminopeptidase 2 variant N392K
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Endoplasmic reticulum aminopeptidase 2 | polymer | 967 | 111530.5 | 2 | UniProt (Q6P179) Pfam (PF17900) Pfam (PF01433) Pfam (PF11838) In PDB | Homo sapiens (human) | Leukocyte-derived arginine aminopeptidase, L-RAP |
2 | C, D, F | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
3 | E | alpha-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81874LD) | |||
4 | A, B | LYSINE | non-polymer | 147.2 | 2 | Chemie (LYS) | |||
5 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
6 | A, B | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 2 | Chemie (MES) | |||
7 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
8 | water | water | 18.0 | 106 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 960 (UniProt: Q6P179)
PDB | External Database | Details |
---|---|---|
Val 2 | Phe 2 | SEE REMARK 999 |
Arg 961 | - | expression tag |
His 962 | - | expression tag |
His 963 | - | expression tag |
His 964 | - | expression tag |
His 965 | - | expression tag |
His 966 | - | expression tag |
His 967 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 223060.9 | |
Branched | Number of molecules | 4 |
Total formula weight | 2021.9 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 1700.5 | |
All* | Total formula weight | 226783.3 |