4E1O
Human histidine decarboxylase complex with Histidine methyl ester (HME)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Histidine decarboxylase | polymer | 481 | 54314.2 | 6 | UniProt (P19113) Pfam (PF00282) | Homo sapiens (human) | HDC |
| 2 | G, I, K, M, O... (A, B, C, D, E...) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 6 | Chemie (PLP) | |||
| 3 | H, J, L, N, P... (A, B, C, D, E...) | HISTIDINE-METHYL-ESTER | non-polymer | 170.2 | 6 | Chemie (PVH) | |||
| 4 | S, T, U, V, W... (A, B, C, D, E...) | water | water | 18.0 | 2039 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 2 - 477 (UniProt: P19113)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
| Ser 180 | Cys 180 | engineered mutation |
| Ser 418 | Cys 418 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 325885.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2504.0 | |
| All* | Total formula weight | 328389.0 |
