4E17

Alpha-E-catenin is an autoinhibited molecule that co-activates vinculin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Vinculin	polymer	263	29379.9	1	UniProt (P12003) Pfam (PF01044) In PDB	Gallus gallus (chicken)
2	B	Catenin alpha-1	polymer	40	4403.8	1	UniProt (P26231) In PDB	Mus musculus (mouse)	Alpha E-catenin, 102 kDa cadherin-associated protein, CAP102
3		water	water		18.0	51	Chemie (HOH)

Sequence modifications

A: 1 - 259 (UniProt: P12003)

PDB	External Database	Details
Gly -3	-	expression tag
Gly -2	-	expression tag
Ile -1	-	expression tag
Gln 0	-	expression tag

B: 321 - 356 (UniProt: P26231)

PDB	External Database	Details
Gly -3	-	expression tag
Gly -2	-	expression tag
Ile -1	-	expression tag
Gln 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	33783.8
All*	Total formula weight	33783.8

*Water molecules are not included.