4DXJ
Crystal structure of Trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(n-propylamino)ethane-1,1-diyl]bisphosphonic acid and Mg2+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Farnesyl pyrophosphate synthase | polymer | 362 | 41225.3 | 3 | UniProt (Q95WL3) Pfam (PF00348) | Trypanosoma cruzi | FPPS, farnesyl diphosphate synthase |
| 2 | D, E, F, K, L... (A, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 9 | Chemie (MG) | |||
| 3 | G, N, W (A, B, C) | [2-(propylamino)ethane-1,1-diyl]bis(phosphonic acid) | non-polymer | 247.1 | 3 | Chemie (0M9) | |||
| 4 | H, O, X (A, B, C) | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE | non-polymer | 246.1 | 3 | Chemie (IPE) | |||
| 5 | AA, I, P, Q, Z (C, A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 5 | Chemie (PEG) | |||
| 6 | J, R (A, B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 7 | S (B) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 8 | Y (C) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 9 | BA, CA, DA (A, B, C) | water | water | 18.0 | 161 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 123676.0 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 2630.3 | |
| All* | Total formula weight | 126306.3 |
