4DXA
Co-crystal structure of Rap1 in complex with KRIT1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ras-related protein Rap-1b | polymer | 169 | 19206.7 | 1 | UniProt (P61224) Pfam (PF00071) | Homo sapiens (human) | GTP-binding protein smg p21B |
| 2 | B (B) | Krev interaction trapped protein 1 | polymer | 322 | 37372.3 | 1 | UniProt (O00522) Pfam (PF00373) | Homo sapiens (human) | Krev interaction trapped 1, Cerebral cavernous malformations 1 protein |
| 3 | C (A) | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE | non-polymer | 539.2 | 1 | Chemie (GSP) | |||
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 327 | Chemie (HOH) |
Sequence modifications
A: 1 - 167 (UniProt: P61224)
B: 420 - 736 (UniProt: O00522)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Val 12 | Gly 12 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 415 | - | expression tag |
| Ser 416 | - | expression tag |
| Pro 417 | - | expression tag |
| Glu 418 | - | expression tag |
| Phe 419 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 56579.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 563.6 | |
| All* | Total formula weight | 57142.6 |
