4DXA
Co-crystal structure of Rap1 in complex with KRIT1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Ras-related protein Rap-1b | polymer | 169 | 19206.7 | 1 | UniProt (P61224) Pfam (PF00071) In PDB | Homo sapiens (human) | GTP-binding protein smg p21B |
2 | B | Krev interaction trapped protein 1 | polymer | 322 | 37372.3 | 1 | UniProt (O00522) Pfam (PF00373) In PDB | Homo sapiens (human) | Krev interaction trapped 1, Cerebral cavernous malformations 1 protein |
3 | A | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE | non-polymer | 539.2 | 1 | Chemie (GSP) | |||
4 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
5 | water | water | 18.0 | 327 | Chemie (HOH) |
Sequence modifications
A: 1 - 167 (UniProt: P61224)
B: 420 - 736 (UniProt: O00522)
PDB | External Database | Details |
---|---|---|
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Val 12 | Gly 12 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 415 | - | expression tag |
Ser 416 | - | expression tag |
Pro 417 | - | expression tag |
Glu 418 | - | expression tag |
Phe 419 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 56579.0 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 563.6 | |
All* | Total formula weight | 57142.6 |