4DX0
Structure of the 14-3-3/PMA2 complex stabilized by a pyrazole derivative
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 14-3-3-like protein E | polymer | 243 | 27485.0 | 1 | UniProt (O49997) Pfam (PF00244) | Nicotiana tabacum (American tobacco tobacco) | |
| 2 | B (P) | N.plumbaginifolia H+-translocating ATPase mRNA | polymer | 31 | 3597.1 | 1 | UniProt (Q42932) | Nicotiana plumbaginifolia (leadwort-leaved tobacco) | |
| 3 | C (A) | 4-[(4R)-4-(4-nitrophenyl)-6-oxidanylidene-3-phenyl-1,4-dihydropyrrolo[3,4-c]pyrazol-5-yl]benzoic acid | non-polymer | 440.4 | 1 | Chemie (0MT) |
Sequence modifications
A: 1 - 238 (UniProt: O49997)
P: 926 - 956 (UniProt: Q42932)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Arg 926 | Gln 926 | conflict |
| Ala 938 | Ser 938 | conflict |
| Asp 955 | Thr 955 | engineered mutation |
| Ile 956 | Val 956 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31082.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 440.4 | |
| All* | Total formula weight | 31522.6 |
