4DWJ

Crystal structure of Thymidylate Kinase from Staphylococcus aureus in complex with Thymidine Monophosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Thymidylate kinase	polymer	229	26198.5	8	UniProt (P65248)	Staphylococcus aureus subsp. aureus	dTMP kinase
2	I, J, K, L, M... (A, B, C, D, F...)	THYMIDINE-5'-PHOSPHATE	non-polymer		322.2	7	Chemie (TMP) PubChem (18531120) PubChem (20711568) PubChem (1139) PubChem (23657880) PubChem (24802545) PubChem (444919) PubChem (44361457) PubChem (25113134) PubChem (51397487) PubChem (5748250) PubChem (9700) PubChem (10147784) PubChem (5274091) PubChem (129069890) PubChem (133126478) PubChem (164603144)
3	P, Q, R, S, T... (A, B, C, D, E...)	water	water		18.0	75	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 1 - 205 (UniProt: P65248)

PDB	External Database	Details
Met -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
Gly -14	-	expression tag
Val -13	-	expression tag
Asp -12	-	expression tag
Leu -11	-	expression tag
Gly -10	-	expression tag
Thr -9	-	expression tag
Glu -8	-	expression tag
Asn -7	-	expression tag
Leu -6	-	expression tag
Tyr -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	209588.1
Non-Polymers*	Number of molecules	7
	Total formula weight	2255.5
All*	Total formula weight	211843.6

*Water molecules are not included.