4DQH
Crystal Structure of (R14C/E65C) HIV-1 Protease in complex with DRV
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Wild-type HIV-1 protease dimer | polymer | 99 | 10687.7 | 2 | UniProt (by SIFTS) (P12499) | Human immunodeficiency virus 1 (HIV-1) | |
| 2 | C (B) | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE | non-polymer | 547.7 | 1 | Chemie (017) | |||
| 3 | D (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 138 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21375.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 639.8 | |
| All* | Total formula weight | 22015.1 |
