4DPY

Crystal structure of Staphylococcus epidermidis S192A mevalonate diphosphate decarboxylase complexed with inhibitor DPGP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Mevalonate diphosphate decarboxylase	polymer	332	36854.4	2	UniProt (Q9FD73) Pfam (PF22700) Pfam (PF18376) In PDB	Staphylococcus epidermidis
2	A, B	1-({[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}acetyl)-L-proline	non-polymer		333.1	2	Chemie (2P0)
3		water	water		18.0	399	Chemie (HOH)

Sequence modifications

A, B: 1 - 327 (UniProt: Q9FD73)

PDB	External Database	Details
Gly -4	-	expression tag
Ser -3	-	expression tag
Thr -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Ala 192	Ser 192	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	73708.8
Non-Polymers*	Number of molecules	2
	Total formula weight	666.3
All*	Total formula weight	74375.0

*Water molecules are not included.