4DPY
Crystal structure of Staphylococcus epidermidis S192A mevalonate diphosphate decarboxylase complexed with inhibitor DPGP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004163 | molecular_function | diphosphomevalonate decarboxylase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0008299 | biological_process | isoprenoid biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| A | 0019287 | biological_process | isopentenyl diphosphate biosynthetic process, mevalonate pathway |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004163 | molecular_function | diphosphomevalonate decarboxylase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0008299 | biological_process | isoprenoid biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016831 | molecular_function | carboxy-lyase activity |
| B | 0019287 | biological_process | isopentenyl diphosphate biosynthetic process, mevalonate pathway |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE 2P0 A 401 |
| Chain | Residue |
| A | ALA14 |
| A | ARG144 |
| A | ALA192 |
| A | ARG193 |
| A | ASP283 |
| A | HOH568 |
| A | HOH570 |
| A | HOH606 |
| A | HOH617 |
| A | HOH690 |
| A | LYS17 |
| A | TYR18 |
| A | LYS21 |
| A | ILE27 |
| A | SER107 |
| A | SER139 |
| A | GLY140 |
| A | SER141 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 2P0 B 401 |
| Chain | Residue |
| B | ALA14 |
| B | TYR18 |
| B | LYS21 |
| B | SER107 |
| B | SER139 |
| B | GLY140 |
| B | SER141 |
| B | ARG144 |
| B | ALA192 |
| B | ARG193 |
| B | ASP283 |
| B | HOH517 |
| B | HOH594 |
| B | HOH661 |
