4DPU
Crystal structure of Staphylococcus epidermidis S192A mevalonate diphosphate decarboxylase complexed with inhibitor 6-FMVAPP and ATPgS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Mevalonate diphosphate decarboxylase | polymer | 332 | 36854.4 | 2 | UniProt (Q9FD73) Pfam (PF00288) Pfam (PF18376) In PDB | Staphylococcus epidermidis | |
| 2 | A, B | (3R)-3-(fluoromethyl)-3-hydroxy-5-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}pentanoic acid | non-polymer | 326.1 | 2 | Chemie (FM0) | |||
| 3 | A, B | PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | non-polymer | 523.2 | 2 | Chemie (AGS) | |||
| 4 | water | water | 18.0 | 488 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 327 (UniProt: Q9FD73)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Thr -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Ala 192 | Ser 192 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 73708.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1698.7 | |
| All* | Total formula weight | 75407.5 |
