4DPU
Crystal structure of Staphylococcus epidermidis S192A mevalonate diphosphate decarboxylase complexed with inhibitor 6-FMVAPP and ATPgS
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Mevalonate diphosphate decarboxylase | polymer | 332 | 36854.4 | 2 | UniProt (Q9FD73) Pfam (PF22700) Pfam (PF18376) In PDB | Staphylococcus epidermidis | |
2 | A, B | (3R)-3-(fluoromethyl)-3-hydroxy-5-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}pentanoic acid | non-polymer | 326.1 | 2 | Chemie (FM0) | |||
3 | A, B | PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | non-polymer | 523.2 | 2 | Chemie (AGS) | |||
4 | water | water | 18.0 | 488 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 327 (UniProt: Q9FD73)
PDB | External Database | Details |
---|---|---|
Gly -4 | - | expression tag |
Ser -3 | - | expression tag |
Thr -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Ala 192 | Ser 192 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 73708.8 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1698.7 | |
All* | Total formula weight | 75407.5 |