4DOU

Crystal Structure of a Single-chain Trimer of Human Adiponectin Globular Domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Adiponectin	polymer	442	51003.2	1	UniProt (Q15848) Pfam (PF00386)	Homo sapiens (Human)	30 kDa adipocyte complement-related protein,Adipocyte complement-related 30 kDa protein,ACRP30,Adipocyte,C1q and collagen domain-containing protein,Adipose most abundant gene transcript 1 protein,apM-1,Gelatin-binding protein,30 kDa adipocyte complement-related protein, Adipocyte complement-related 30 kDa protein, ACRP30, Adipocyte, C1q and collagen domain-containing protein, Adipose most abundant gene transcript 1 protein, apM-1, Gelatin-binding protein
2	B, C, D (A)	CALCIUM ION	non-polymer		40.1	3	Chemie (CA)
3	E (A)	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
4	F (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5	G, H, I, J, K (A)	1,2-ETHANEDIOL	non-polymer		62.1	5	Chemie (EDO)
6	L (A)	water	water		18.0	158	Chemie (HOH)

Sequence modifications

A: 104 - 244 (UniProt: Q15848)

PDB	External Database	Details
His 87	-	expression tag
His 88	-	expression tag
His 89	-	expression tag
His 90	-	expression tag
His 91	-	expression tag
His 92	-	expression tag
His 93	-	expression tag
His 94	-	expression tag
Glu 95	-	expression tag
Asn 96	-	expression tag
Leu 97	-	expression tag
Tyr 98	-	expression tag
Phe 99	-	expression tag
Gln 100	-	expression tag
Gly 101	-	expression tag
Ala 102	-	expression tag
Ser 103	-	expression tag

A: 245 - 528 (PDB: 4DOU)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	51003.2
Non-Polymers*	Number of molecules	10
	Total formula weight	545.7
All*	Total formula weight	51548.9

*Water molecules are not included.