4DMK

Crystal structure of the CFTR inhibitory factor Cif with the Y239F mutation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Putative hydrolase	polymer	301	34148.7	4	UniProt (Q02P97) Pfam (PF12697) UniProt (by SIFTS) (A0A0H2ZD27)	Pseudomonas aeruginosa
2	E, F, G, H (A, B, C, D)	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
3	I, J, K, L (A, B, C, D)	water	water		18.0	1250	Chemie (HOH)

Sequence modifications

A, B, C, D: 25 - 319 (UniProt: Q02P97)

PDB	External Database	Details
Phe 239	Tyr 239	engineered mutation
His 320	-	expression tag
His 321	-	expression tag
His 322	-	expression tag
His 323	-	expression tag
His 324	-	expression tag
His 325	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	136594.8
Non-Polymers*	Number of molecules	4
	Total formula weight	368.4
All*	Total formula weight	136963.2

*Water molecules are not included.