4DMK
Crystal structure of the CFTR inhibitory factor Cif with the Y239F mutation
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004301 | molecular_function | epoxide hydrolase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0043657 | cellular_component | host cell |
| B | 0004301 | molecular_function | epoxide hydrolase activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0043657 | cellular_component | host cell |
| C | 0004301 | molecular_function | epoxide hydrolase activity |
| C | 0005576 | cellular_component | extracellular region |
| C | 0043657 | cellular_component | host cell |
| D | 0004301 | molecular_function | epoxide hydrolase activity |
| D | 0005576 | cellular_component | extracellular region |
| D | 0043657 | cellular_component | host cell |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GOL A 401 |
| Chain | Residue |
| A | ASP129 |
| A | HOH653 |
| A | HOH682 |
| A | GLU153 |
| A | ALA154 |
| A | PRO155 |
| A | VAL175 |
| A | PHE178 |
| A | HIS207 |
| A | HIS297 |
| A | HOH529 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL B 401 |
| Chain | Residue |
| B | ASP129 |
| B | GLU153 |
| B | ALA154 |
| B | HIS177 |
| B | PHE178 |
| B | PHE239 |
| B | HIS297 |
| B | HOH608 |
| B | HOH792 |
| B | HOH795 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL C 401 |
| Chain | Residue |
| C | ASP129 |
| C | GLU153 |
| C | ALA154 |
| C | PRO155 |
| C | VAL175 |
| C | HIS207 |
| C | HIS297 |
| C | HOH531 |
| C | HOH646 |
| C | HOH677 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL D 401 |
| Chain | Residue |
| D | ASP129 |
| D | GLU153 |
| D | PRO155 |
| D | HIS207 |
| D | HIS297 |
| D | HOH567 |
| D | HOH664 |
| D | HOH783 |
