4DLQ

Crystal structure of the GAIN and HormR domains of CIRL 1/Latrophilin 1 (CL1)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Latrophilin-1	polymer	381	41947.5	1	UniProt (O88917) Pfam (PF02793) Pfam (PF16489) Pfam (PF01825) In PDB	Rattus norvegicus (rat)	Calcium-independent alpha-latrotoxin receptor 1, CIRL-1
2	B	Latrophilin-1	polymer	18	2257.6	1	UniProt (O88917) In PDB	Rattus norvegicus (rat)	Calcium-independent alpha-latrotoxin receptor 1, CIRL-1
3	C	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
4	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)
5	A	SULFATE ION	non-polymer		96.1	8	Chemie (SO4)
6	A	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
7		water	water		18.0	275	Chemie (HOH)

Sequence modifications

A: 460 - 837 (UniProt: O88917)

PDB	External Database	Details
Ala 457	-	expression tag
Asp 458	-	expression tag
Pro 459	-	expression tag

B: 838 - 850 (UniProt: O88917)

PDB	External Database	Details
His 851	-	expression tag
His 852	-	expression tag
His 853	-	expression tag
His 854	-	expression tag
His 855	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	44205.0
Branched	Number of molecules	1
	Total formula weight	424.4
Non-Polymers*	Number of molecules	14
	Total formula weight	1837.5
All*	Total formula weight	46467.0

*Water molecules are not included.