4DL8
Crystal structure of Trypanosoma brucei dUTPase with dUMP, planar [AlF3-OPO3] transition state analogue, Mg2+, and Na+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Deoxyuridine triphosphatase | polymer | 290 | 32204.3 | 1 | UniProt (Q57ZH3) Pfam (PF08761) | Trypanosoma brucei | deoxyuridine triphosphate nucleotidohydrolase |
| 2 | B (A) | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE | non-polymer | 308.2 | 1 | Chemie (UMP) PubChem (688) PubChem (65063) PubChem (446899) PubChem (446900) PubChem (57164254) PubChem (71773959) PubChem (92144438) PubChem (92209480) PubChem (92209481) PubChem (92209482) PubChem (92449733) PubChem (133126534) | |||
| 3 | C (A) | ALUMINUM FLUORIDE | non-polymer | 84.0 | 1 | Chemie (AF3) PubChem (2124) | |||
| 4 | D (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) PubChem (1061) | |||
| 5 | E, F (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 6 | G (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) PubChem (923) | |||
| 7 | H (A) | water | water | 18.0 | 166 | Chemie (HOH) |
Sequence modifications
A: 1 - 287 (UniProt: Q57ZH3)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32204.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 558.7 | |
| All* | Total formula weight | 32763.0 |
