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4DL3

Human DNA polymerase eta inserting dCMPNPP opposite GG template (GG0b).

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase etapolymer43548617.71UniProt (Q9Y253)
Pfam (PF00817)
Pfam (PF21704)
Pfam (PF11799)
Homo sapiens (human)RAD30 homolog A, Xeroderma pigmentosum variant type protein
2B
(T)
DNA (5'-D(*TP*AP*CP*GP*GP*TP*CP*AP*CP*AP*CP*T)-3')polymer123622.41
3C
(P)
DNA (5'-D(*TP*AP*GP*TP*GP*TP*GP*AP*C)-3')polymer92770.81
4D, E
(A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
5F, G, H
(A)
GLYCEROLnon-polymer92.13Chemie (GOL)
6I
(P)
2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidinenon-polymer466.21Chemie (0KX)
7J, K, L
(A, T, P)
waterwater18.0277Chemie (HOH)
Sequence modifications
A: 1 - 432 (UniProt: Q9Y253)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight55010.9
Non-Polymers*Number of molecules6
Total formula weight791.1
All*Total formula weight55802.0
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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