4DL3

Human DNA polymerase eta inserting dCMPNPP opposite GG template (GG0b).

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003684	molecular_function	damaged DNA binding
A	0006281	biological_process	DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 501

Chain	Residue
A	ASP13
A	MET14
A	ASP115
P	0KX10

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 502

Chain	Residue
P	0KX10
A	ASP13
A	ASP115
A	GLU116
A	HOH615
P	DC9

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site_id	AC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL A 503

Chain	Residue
A	ARG24
A	GLN25
A	PRO244
A	SER248
A	GLY276
A	GLU277
A	HOH605
A	HOH621
A	HOH743

---

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 504

Chain	Residue
A	GLN20
A	GLN23
A	ARG24
A	ARG30
A	GLY209
A	HOH649
A	HOH653

---

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 505

Chain	Residue
A	ASN26
A	PRO27
A	HIS28
A	GLY271
A	TYR274
A	GLU277
A	HOH798

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site_id	AC6
Number of Residues	24
Details	BINDING SITE FOR RESIDUE 0KX P 10

Chain	Residue
A	ASP13
A	MET14
A	ASP15
A	CYS16
A	PHE17
A	PHE18
A	ILE48
A	TYR52
A	ARG55
A	ARG61
A	ASP115
A	LYS231
A	MG501
A	MG502
A	HOH615
A	HOH620
A	HOH638
A	HOH672
A	HOH818
A	HOH845
P	DC9
P	HOH101
T	DG4
T	DG5

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27284197","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5KFO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27284197","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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