4DKJ

CpG specific methyltransferase in complex with target DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Cytosine-specific methyltransferase	polymer	403	47310.1	1	UniProt (Q8EVR5) Pfam (PF00145)	Mycoplasma penetrans
2	B (B)	DNA (5'-D(*CP*CP*AP*CP*AP*TP*GP*(C37)P*GP*CP*TP*GP*AP*A)-3')	polymer	14	4267.8	1
3	C (C)	DNA (5'-D(*GP*TP*TP*CP*AP*GP*(5CM)P*GP*CP*AP*TP*GP*TP*G)-3')	polymer	14	4325.8	1
4	D (A)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	1	Chemie (SAH)
5	E (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
6	F, G, H (A, B, C)	water	water		18.0	267	Chemie (HOH)

Sequence modifications

A: 1 - 395 (UniProt: Q8EVR5)

PDB	External Database	Details
Arg 68	Gln 68	SEE REMARK 999
Arg 71	Lys 71	SEE REMARK 999
Pro 295	Ser 295	engineered mutation
Leu 396	-	expression tag
Glu 397	-	expression tag
His 398	-	expression tag
His 399	-	expression tag
His 400	-	expression tag
His 401	-	expression tag
His 402	-	expression tag
His 403	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	55903.7
Non-Polymers*	Number of molecules	2
	Total formula weight	476.5
All*	Total formula weight	56380.2

*Water molecules are not included.