4DG0
Crystal structure of myristoylated WT catalytic subunit of cAMP-dependent protein kinase in complex with SP20 and AMP-PNP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | E | cAMP-dependent protein kinase catalytic subunit alpha | polymer | 350 | 40737.3 | 1 | UniProt (P05132) Pfam (PF00069) In PDB | Mus musculus (mouse) | PKA C-alpha |
2 | I | cAMP-dependent protein kinase inhibitor alpha | polymer | 20 | 2199.4 | 1 | UniProt (P63248) In PDB | Mus musculus | PKI-alpha, cAMP-dependent protein kinase inhibitor, muscle/brain isoform |
3 | E | MYRISTIC ACID | non-polymer | 228.4 | 1 | Chemie (MYR) | |||
4 | E | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
5 | E | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
6 | water | water | 18.0 | 344 | Chemie (HOH) |
Sequence modifications
I: 5 - 24 (UniProt: P63248)
PDB | External Database | Details |
---|---|---|
Ala 20 | Asn 21 | ENGINEERED MUTATION |
Ser 21 | Ala 22 | ENGINEERED MUTATION |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 42936.7 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 783.2 | |
All* | Total formula weight | 43719.9 |