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4DFM

Crystal structure of the large fragment of DNA polymerase I from Thermus aquaticus in ternary complex with 5-(aminopentinyl)-2-dCTP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase I, thermostablepolymer54060937.01UniProt (P19821)
Pfam (PF09281)
Pfam (PF00476)
Thermus aquaticusTaq polymerase 1
2B
(B)
5'-d(GACCACGGCGC ddG)-3'polymer123657.41
3C
(C)
5'-d(AAAGCGCGCCGTGGTC)-3'polymer164924.21
4D
(A)
5-(5-aminopent-1-yn-1-yl)-2'-deoxycytidine 5'-(tetrahydrogen triphosphate)non-polymer550.31Chemie (0L6)
5E, F, H, N
(A, B)
MAGNESIUM IONnon-polymer24.34Chemie (MG)
6G
(A)
FORMIC ACIDnon-polymer46.01Chemie (FMT)
7I, J, K, L, M
(A)
1,2-ETHANEDIOLnon-polymer62.15Chemie (EDO)
8O, P, Q
(A, B, C)
waterwater18.0248Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight69518.6
Non-Polymers*Number of molecules11
Total formula weight1003.9
All*Total formula weight70522.4
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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