4DEY

Crystal structure of the Voltage Dependent Calcium Channel beta-2 Subunit in Complex With The CaV1.2 I-II Linker.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B	Voltage-dependent L-type calcium channel subunit alpha-1C	polymer	106	12304.4	1	UniProt (P15381) In PDB	Oryctolagus cuniculus (European rabbit Japanese white rabbit domestic rabbit rabbits)	Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle, Smooth muscle calcium channel blocker receptor, CACB-receptor, Voltage-gated calcium channel subunit alpha Cav1.2
2	A	Voltage-dependent L-type calcium channel subunit beta-2	polymer	337	38280.9	1	UniProt (P54288) Pfam (PF12052) Pfam (PF00625) In PDB	Oryctolagus cuniculus (European rabbit Japanese white rabbit domestic rabbit rabbits)	CAB2, Calcium channel voltage-dependent subunit beta 2
3	B, A	BROMIDE ION	non-polymer		79.9	17	Chemie (BR)
4		water	water		18.0	158	Chemie (HOH)

Sequence modifications

B: 435 - 539 (UniProt: P15381)

PDB	External Database	Details
Gly 434	-	expression tag

A: 25 - 137 (UniProt: P54288)
A: 203 - 422 (UniProt: P54288)

PDB	External Database	Details
Glu 138	-	SEE REMARK 999
Phe 139	-	SEE REMARK 999
Lys 140	-	SEE REMARK 999
Leu 141	-	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	50585.3
Non-Polymers*	Number of molecules	17
	Total formula weight	1358.4
All*	Total formula weight	51943.7

*Water molecules are not included.