4DEU
Crystal Structure of the Wild Type TTR Binding Naringenin (TTRwt:NAR)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (A, B) | Transthyretin | polymer | 117 | 12774.3 | 2 | UniProt (P02766) Pfam (PF00576) | Homo sapiens (human) | ATTR, Prealbumin, TBPA |
2 | C, D, E, F, H... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 10 | Chemie (EDO) | |||
3 | G, L (A, B) | NARINGENIN | non-polymer | 272.3 | 2 | Chemie (NAR) | |||
4 | M (B) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
5 | P, Q (A, B) | water | water | 18.0 | 218 | Chemie (HOH) |
Sequence modifications
A, B: 10 - 125 (UniProt: P02766)
PDB | External Database | Details |
---|---|---|
Ala 9 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 25548.6 | |
Non-Polymers* | Number of molecules | 13 |
Total formula weight | 1205.3 | |
All* | Total formula weight | 26753.9 |