4DDL
PDE10a Crystal Structure Complexed with Novel Inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | polymer | 338 | 38889.6 | 2 | UniProt (Q9Y233) | Homo sapiens (human) | |
| 2 | C, D, M, N (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | E, F, G, H, I... (A, B) | SULFATE ION | non-polymer | 96.1 | 15 | Chemie (SO4) | |||
| 4 | L, W (A, B) | 2-{1-[5-(6,7-dimethoxycinnolin-4-yl)-3-methylpyridin-2-yl]piperidin-4-yl}propan-2-ol | non-polymer | 422.5 | 2 | Chemie (0JQ) | |||
| 5 | X, Y (A, B) | water | water | 18.0 | 316 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 77779.2 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 2547.6 | |
| All* | Total formula weight | 80326.8 |
