4DD8
ADAM-8 metalloproteinase domain with bound batimastat
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Disintegrin and metalloproteinase domain-containing protein 8 | polymer | 208 | 23354.3 | 4 | UniProt (P78325) Pfam (PF01421) | Homo sapiens (human) | ADAM 8, Cell surface antigen MS2 |
| 2 | E, M, S, Y (A, B, C, D) | 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE | non-polymer | 477.6 | 4 | Chemie (BAT) | |||
| 3 | F, N, T, Z (A, B, C, D) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 4 | AA, G, O, U (D, A, B, C) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 5 | BA, DA, H, J, P... (D, A, B, C) | SODIUM ION | non-polymer | 23.0 | 8 | Chemie (NA) | |||
| 6 | CA, I, Q, W (D, A, B, C) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 7 | K, L (A) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 8 | EA, FA, GA, HA (A, B, C, D) | water | water | 18.0 | 415 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 93417.2 | |
| Non-Polymers* | Number of molecules | 26 |
| Total formula weight | 2736.4 | |
| All* | Total formula weight | 96153.6 |
