Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004222 | molecular_function | metalloendopeptidase activity |
A | 0006508 | biological_process | proteolysis |
A | 0008237 | molecular_function | metallopeptidase activity |
B | 0004222 | molecular_function | metalloendopeptidase activity |
B | 0006508 | biological_process | proteolysis |
B | 0008237 | molecular_function | metallopeptidase activity |
C | 0004222 | molecular_function | metalloendopeptidase activity |
C | 0006508 | biological_process | proteolysis |
C | 0008237 | molecular_function | metallopeptidase activity |
D | 0004222 | molecular_function | metalloendopeptidase activity |
D | 0006508 | biological_process | proteolysis |
D | 0008237 | molecular_function | metallopeptidase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 15 |
Details | BINDING SITE FOR RESIDUE BAT A 1000 |
Chain | Residue |
A | THR299 |
A | ALA365 |
A | GLY366 |
A | SER367 |
A | ILE368 |
A | ZN1002 |
A | CL1004 |
A | THR300 |
A | VAL301 |
A | GLY302 |
A | PHE303 |
A | HIS334 |
A | GLU335 |
A | HIS338 |
A | HIS344 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA A 1001 |
Chain | Residue |
A | GLU203 |
A | ASP286 |
A | CYS395 |
A | ASN398 |
A | HOH1101 |
A | HOH1102 |
site_id | AC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN A 1002 |
Chain | Residue |
A | HIS334 |
A | HIS338 |
A | HIS344 |
A | BAT1000 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE NA A 1003 |
Chain | Residue |
A | ILE368 |
A | SER371 |
A | HOH1103 |
A | HOH1104 |
A | HOH1105 |
site_id | AC5 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CL A 1004 |
Chain | Residue |
A | ALA304 |
A | HIS338 |
A | BAT1000 |
site_id | AC6 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE NA A 1005 |
Chain | Residue |
A | ASP295 |
A | PHE296 |
A | GLY298 |
A | HOH1106 |
site_id | AC7 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE K A 1006 |
Chain | Residue |
A | HOH1107 |
A | HOH1120 |
site_id | AC8 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE K A 1007 |
Chain | Residue |
A | ASP343 |
A | ASP345 |
A | SER380 |
A | HOH1109 |
site_id | AC9 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE BAT B 1000 |
Chain | Residue |
B | THR299 |
B | THR300 |
B | VAL301 |
B | GLY302 |
B | HIS334 |
B | GLU335 |
B | HIS338 |
B | HIS344 |
B | ALA365 |
B | GLY366 |
B | SER367 |
B | ILE368 |
B | ZN1002 |
B | CL1004 |
site_id | BC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CA B 1001 |
Chain | Residue |
B | GLU203 |
B | ASP286 |
B | CYS395 |
B | ASN398 |
B | HOH1101 |
site_id | BC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN B 1002 |
Chain | Residue |
B | HIS334 |
B | HIS338 |
B | HIS344 |
B | BAT1000 |
site_id | BC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE NA B 1003 |
Chain | Residue |
B | ILE368 |
B | SER371 |
B | HOH1102 |
B | HOH1103 |
B | HOH1104 |
site_id | BC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL B 1004 |
Chain | Residue |
B | ALA304 |
B | GLU335 |
B | HIS338 |
B | BAT1000 |
site_id | BC5 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE NA B 1005 |
Chain | Residue |
B | ASP295 |
B | PHE296 |
B | GLY298 |
B | HOH1105 |
B | HOH1106 |
site_id | BC6 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE BAT C 1000 |
Chain | Residue |
B | PHE258 |
C | THR299 |
C | THR300 |
C | VAL301 |
C | GLY302 |
C | HIS334 |
C | GLU335 |
C | HIS338 |
C | HIS344 |
C | ALA365 |
C | GLY366 |
C | SER367 |
C | ILE368 |
C | ZN1002 |
C | CL1004 |
C | HOH1131 |
site_id | BC7 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CA C 1001 |
Chain | Residue |
C | ASN398 |
C | HOH1101 |
C | GLU203 |
C | ASP286 |
C | CYS395 |
site_id | BC8 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN C 1002 |
Chain | Residue |
C | HIS334 |
C | HIS338 |
C | HIS344 |
C | BAT1000 |
site_id | BC9 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE NA C 1003 |
Chain | Residue |
C | ILE368 |
C | SER371 |
C | HOH1102 |
C | HOH1103 |
C | HOH1104 |
site_id | CC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CL C 1004 |
Chain | Residue |
C | ALA304 |
C | GLU335 |
C | HIS338 |
C | BAT1000 |
C | HOH1185 |
site_id | CC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE NA C 1005 |
Chain | Residue |
C | ASP295 |
C | PHE296 |
C | GLY298 |
C | HOH1105 |
site_id | CC3 |
Number of Residues | 18 |
Details | BINDING SITE FOR RESIDUE BAT D 1000 |
Chain | Residue |
A | GLN255 |
A | ASP256 |
A | ARG257 |
A | HOH1125 |
D | THR299 |
D | THR300 |
D | VAL301 |
D | GLY302 |
D | HIS334 |
D | GLU335 |
D | HIS338 |
D | HIS344 |
D | ALA365 |
D | GLY366 |
D | SER367 |
D | ILE368 |
D | ZN1002 |
D | CL1004 |
site_id | CC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA D 1001 |
Chain | Residue |
D | GLU203 |
D | ASP286 |
D | CYS395 |
D | ASN398 |
D | HOH1103 |
D | HOH1194 |
site_id | CC5 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN D 1002 |
Chain | Residue |
D | HIS334 |
D | HIS338 |
D | HIS344 |
D | BAT1000 |
site_id | CC6 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE NA D 1003 |
Chain | Residue |
D | ARG361 |
D | ILE368 |
D | SER371 |
D | HOH1104 |
D | HOH1105 |
D | HOH1106 |
site_id | CC7 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CL D 1004 |
Chain | Residue |
D | ALA304 |
D | BAT1000 |
D | HOH1147 |
site_id | CC8 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE NA D 1005 |
Chain | Residue |
D | ASP295 |
D | PHE296 |
D | GLY298 |
D | HOH1107 |
D | HOH1108 |
D | HOH1109 |
Functional Information from PROSITE/UniProt
site_id | PS00142 |
Number of Residues | 10 |
Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. TMAHEMGHNL |
Chain | Residue | Details |
A | THR331-LEU340 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | GLU335 | |
B | GLU335 | |
C | GLU335 | |
D | GLU335 | |
Chain | Residue | Details |
A | HIS334 | |
D | HIS334 | |
D | HIS338 | |
D | HIS344 | |
A | HIS338 | |
A | HIS344 | |
B | HIS334 | |
B | HIS338 | |
B | HIS344 | |
C | HIS334 | |
C | HIS338 | |
C | HIS344 | |