4DCB

Y. pestis Plasminogen Activator Pla in Complex with Human Plasminogen Activation Loop Peptide ALP11

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Coagulase/fibrinolysin	polymer	297	33281.3	1	UniProt (P17811) Pfam (PF01278)	Yersinia pestis	Plasminogen activator
2	B (F)	Plasminogen	polymer	11	1106.4	1	UniProt (P00747)	Homo sapiens	Plasmin heavy chain A, Activation peptide, Angiostatin, Plasmin heavy chain A, short form, Plasmin light chain B
3	C, D, E, F (A)	(4R)-2-METHYLPENTANE-2,4-DIOL	non-polymer		118.2	4	Chemie (MRD)
4	G, H (A)	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	2	Chemie (MPD)
5	I (A)	(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE	non-polymer		306.4	1	Chemie (C8E)
6	J (A)	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
7	K (A)	water	water		18.0	106	Chemie (HOH)

Sequence modifications

A: 5 - 292 (UniProt: P17811)

PDB	External Database	Details
Asn 84	Asp 104	engineered mutation
Gly 293	-	expression tag
Gly 294	-	expression tag
Gly 295	-	expression tag
His 296	-	expression tag
His 297	-	expression tag
His 298	-	expression tag
His 299	-	expression tag
His 300	-	expression tag
His 301	-	expression tag

F: 557 - 566 (UniProt: P00747)

PDB	External Database	Details
Lys 567	-	insertion

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	34387.7
Non-Polymers*	Number of molecules	8
	Total formula weight	1110.5
All*	Total formula weight	35498.2

*Water molecules are not included.