4D52

CRYSTAL STRUCTURE OF FUCOSE BINDING LECTIN FROM ASPERGILLUS FUMIGATUS (AFL) IN COMPLEX WITH L-GALACTOPYRANOSE.

Replaces:  4UQ7Replaces:  4AHB

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	FUCOSE-SPECIFIC LECTIN FLEA	polymer	315	34612.5	1	UniProt (Q4WW81) Pfam (PF07938)	ASPERGILLUS FUMIGATUS	AFL
2	B, D (B, D)	FUCOSE-SPECIFIC LECTIN FLEA	polymer	315	34644.5	2	UniProt (Q4WW81) Pfam (PF07938)	ASPERGILLUS FUMIGATUS	AFL
3	C (C)	FUCOSE-SPECIFIC LECTIN FLEA	polymer	315	34676.5	1	UniProt (Q4WW81) Pfam (PF07938)	ASPERGILLUS FUMIGATUS	AFL
4	BA, DA, E, EA, H... (C, A, D, B)	alpha-L-galactopyranose	non-polymer		180.2	14	Chemie (GXL)
5	F, KA, LA, M, MA... (A, C, D, B)	beta-L-galactopyranose	non-polymer		180.2	12	Chemie (GIV)
6	CA, G, IA, K, R... (C, A, B, D)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	7	Chemie (PEG)
7	FA, GA, J, RA, U (C, A, D, B)	TETRAETHYLENE GLYCOL	non-polymer		194.2	5	Chemie (PG4)
8	O (B)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
9	AA, NA, P (C, D, B)	SODIUM ION	non-polymer		23.0	3	Chemie (NA)
10	HA, SA, V (C, D, B)	TRIETHYLENE GLYCOL	non-polymer		150.2	3	Chemie (PGE)
11	AB, XA, YA, ZA (D, A, B, C)	water	water		18.0	1060	Chemie (HOH)

Sequence modifications

A: 1 - 315 (UniProt: Q4WW81)

PDB	External Database	Details
Ser 20	Leu 20	conflict
Cys 111	Arg 111	conflict

B, D: 1 - 315 (UniProt: Q4WW81)

PDB	External Database	Details
Ser 20	Leu 20	conflict
Csd 111	Arg 111	conflict

C: 1 - 315 (UniProt: Q4WW81)

PDB	External Database	Details
Ser 20	Leu 20	conflict
Csd 111	Arg 111	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	138577.8
Non-Polymers*	Number of molecules	45
	Total formula weight	6982.9
All*	Total formula weight	145560.8

*Water molecules are not included.