4D4S

Focal Adhesion Kinase catalytic domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	FOCAL ADHESION KINASE 1	polymer	276	31731.8	2	UniProt (Q00944) Pfam (PF07714)	GALLUS GALLUS (CHICKEN)	FADK 1, FOCAL ADHESION KINASE-RELATED NONKINASE, FRNK, P41/P43FRNK, PROTEIN-TYROSINE KINASE 2, P125FAK, PP125FAK
2	C, D, F, G (A, B)	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
3	E, H (A, B)	DIMETHYL SULFOXIDE	non-polymer		78.1	2	Chemie (DMS)
4	I (B)	2-({5-CHLORO-2-[(2-METHOXY-4-MORPHOLIN-4-YLPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)-N-METHYLBENZAMIDE	non-polymer		468.9	1	Chemie (BI9)
5	J, K (A, B)	water	water		18.0	148	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	63463.6
Non-Polymers*	Number of molecules	7
	Total formula weight	1009.5
All*	Total formula weight	64473.1

*Water molecules are not included.