4D2N
Crystal structure of deglycosylated serum-derived human IgG4 Fc
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | IG GAMMA-4 CHAIN C REGION | polymer | 226 | 25448.7 | 4 | UniProt (P01861) Pfam (PF07654) | HOMO SAPIENS (HUMAN) | |
| 2 | E (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | F, G, H (A, B, C) | water | water | 18.0 | 12 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 222 - 447 (UniProt: P01861)
| PDB | External Database | Details |
|---|---|---|
| Asp 297 | Asn 177 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 101794.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 101886.7 |
