4D2E
Crystal structure of an integral membrane kinase - v2.3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | DIACYLGLYCEROL KINASE | polymer | 130 | 14204.5 | 6 | UniProt (P0ABN1) Pfam (PF01219) | ESCHERICHIA COLI K-12 | DAGK, DIGLYCERIDE KINASE, DGK |
| 2 | G, H, I, J, O... (A, C, D) | (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE | non-polymer | 314.5 | 7 | Chemie (78M) | |||
| 3 | AA, BA, K, L, M... (D, E, A, B, C) | (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE | non-polymer | 314.5 | 11 | Chemie (78N) | |||
| 4 | U (D) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | V, W (D) | CITRATE ANION | non-polymer | 189.1 | 2 | Chemie (FLC) | |||
| 6 | Y (D) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 7 | CA, DA, EA, FA, GA... (A, B, C, D, E...) | water | water | 18.0 | 144 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 121 (UniProt: P0ABN1)
| PDB | External Database | Details |
|---|---|---|
| Gly -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| Glu -1 | - | expression tag |
| Leu 0 | - | expression tag |
| Cys 41 | Ala 42 | engineered mutation |
| Ala 46 | Cys 47 | engineered mutation |
| Val 53 | Ile 54 | engineered mutation |
| Leu 70 | Ile 71 | engineered mutation |
| Leu 96 | Met 97 | engineered mutation |
| Asp 107 | Val 108 | engineered mutation |
| Ala 113 | Cys 114 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 85226.7 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 6126.9 | |
| All* | Total formula weight | 91353.6 |
