4D0T
GalNAc-T2 crystal soaked with UDP-GalNAc, EA2 peptide and manganese
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 2 | polymer | 571 | 64824.7 | 6 | UniProt (Q10471) Pfam (PF00535) Pfam (PF00652) | HOMO SAPIENS (HUMAN) | POLYPEPTIDE GALNAC TRANSFERASE 2, GALNAC-T2, PP-GANTASE 2, PROTEIN-UDP ACETYLGALACTOSAMINYLTRANSFERASE 2, UDP-GALNAC, POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 2, POLYPEPTIDE GALNAC-TRANSFERASE T2 |
| 2 | G, H (P, Z) | PEPTIDE | polymer | 8 | 788.8 | 2 | SYNTHETIC CONSTRUCT | ||
| 3 | CA, I, M, Q, U... (F, A, B, C, D...) | MANGANESE (II) ION | non-polymer | 54.9 | 6 | Chemie (MN) | |||
| 4 | AA, BA, J, K, N... (E, A, B, C, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 10 | Chemie (EDO) | |||
| 5 | DA, L, P, V, Z (F, A, B, D, E) | URIDINE-DIPHOSPHATE-N-ACETYLGALACTOSAMINE | non-polymer | 607.4 | 5 | Chemie (UD2) | |||
| 6 | R (C) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 1 | Chemie (UDP) | |||
| 7 | EA (P) | 2-acetamido-2-deoxy-beta-D-galactopyranose | non-polymer | 221.2 | 1 | Chemie (NGA) | |||
| 8 | FA, GA, HA, IA, JA... (A, B, C, D, E...) | water | water | 18.0 | 469 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 571 (UniProt: Q10471)
| PDB | External Database | Details |
|---|---|---|
| Asp 516 | Asn 516 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 390525.8 | |
| Non-Polymers* | Number of molecules | 23 |
| Total formula weight | 4612.4 | |
| All* | Total formula weight | 395138.3 |
