4D0T

GalNAc-T2 crystal soaked with UDP-GalNAc, EA2 peptide and manganese

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000139	cellular_component	Golgi membrane
A	0002639	biological_process	positive regulation of immunoglobulin production
A	0004653	molecular_function	polypeptide N-acetylgalactosaminyltransferase activity
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005789	cellular_component	endoplasmic reticulum membrane
A	0005794	cellular_component	Golgi apparatus
A	0005795	cellular_component	Golgi stack
A	0006486	biological_process	obsolete protein glycosylation
A	0006493	biological_process	protein O-linked glycosylation
A	0016020	cellular_component	membrane
A	0016266	biological_process	protein O-linked glycosylation via N-acetyl-galactosamine
A	0016740	molecular_function	transferase activity
A	0016757	molecular_function	glycosyltransferase activity
A	0018243	biological_process	obsolete protein O-linked glycosylation via threonine
A	0030145	molecular_function	manganese ion binding
A	0030246	molecular_function	carbohydrate binding
A	0032580	cellular_component	Golgi cisterna membrane
A	0046872	molecular_function	metal ion binding
A	0048471	cellular_component	perinuclear region of cytoplasm
A	0051604	biological_process	protein maturation
B	0000139	cellular_component	Golgi membrane
B	0002639	biological_process	positive regulation of immunoglobulin production
B	0004653	molecular_function	polypeptide N-acetylgalactosaminyltransferase activity
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005789	cellular_component	endoplasmic reticulum membrane
B	0005794	cellular_component	Golgi apparatus
B	0005795	cellular_component	Golgi stack
B	0006486	biological_process	obsolete protein glycosylation
B	0006493	biological_process	protein O-linked glycosylation
B	0016020	cellular_component	membrane
B	0016266	biological_process	protein O-linked glycosylation via N-acetyl-galactosamine
B	0016740	molecular_function	transferase activity
B	0016757	molecular_function	glycosyltransferase activity
B	0018243	biological_process	obsolete protein O-linked glycosylation via threonine
B	0030145	molecular_function	manganese ion binding
B	0030246	molecular_function	carbohydrate binding
B	0032580	cellular_component	Golgi cisterna membrane
B	0046872	molecular_function	metal ion binding
B	0048471	cellular_component	perinuclear region of cytoplasm
B	0051604	biological_process	protein maturation
C	0000139	cellular_component	Golgi membrane
C	0002639	biological_process	positive regulation of immunoglobulin production
C	0004653	molecular_function	polypeptide N-acetylgalactosaminyltransferase activity
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005789	cellular_component	endoplasmic reticulum membrane
C	0005794	cellular_component	Golgi apparatus
C	0005795	cellular_component	Golgi stack
C	0006486	biological_process	obsolete protein glycosylation
C	0006493	biological_process	protein O-linked glycosylation
C	0016020	cellular_component	membrane
C	0016266	biological_process	protein O-linked glycosylation via N-acetyl-galactosamine
C	0016740	molecular_function	transferase activity
C	0016757	molecular_function	glycosyltransferase activity
C	0018243	biological_process	obsolete protein O-linked glycosylation via threonine
C	0030145	molecular_function	manganese ion binding
C	0030246	molecular_function	carbohydrate binding
C	0032580	cellular_component	Golgi cisterna membrane
C	0046872	molecular_function	metal ion binding
C	0048471	cellular_component	perinuclear region of cytoplasm
C	0051604	biological_process	protein maturation
D	0000139	cellular_component	Golgi membrane
D	0002639	biological_process	positive regulation of immunoglobulin production
D	0004653	molecular_function	polypeptide N-acetylgalactosaminyltransferase activity
D	0005515	molecular_function	protein binding
D	0005576	cellular_component	extracellular region
D	0005789	cellular_component	endoplasmic reticulum membrane
D	0005794	cellular_component	Golgi apparatus
D	0005795	cellular_component	Golgi stack
D	0006486	biological_process	obsolete protein glycosylation
D	0006493	biological_process	protein O-linked glycosylation
D	0016020	cellular_component	membrane
D	0016266	biological_process	protein O-linked glycosylation via N-acetyl-galactosamine
D	0016740	molecular_function	transferase activity
D	0016757	molecular_function	glycosyltransferase activity
D	0018243	biological_process	obsolete protein O-linked glycosylation via threonine
D	0030145	molecular_function	manganese ion binding
D	0030246	molecular_function	carbohydrate binding
D	0032580	cellular_component	Golgi cisterna membrane
D	0046872	molecular_function	metal ion binding
D	0048471	cellular_component	perinuclear region of cytoplasm
D	0051604	biological_process	protein maturation
E	0000139	cellular_component	Golgi membrane
E	0002639	biological_process	positive regulation of immunoglobulin production
E	0004653	molecular_function	polypeptide N-acetylgalactosaminyltransferase activity
E	0005515	molecular_function	protein binding
E	0005576	cellular_component	extracellular region
E	0005789	cellular_component	endoplasmic reticulum membrane
E	0005794	cellular_component	Golgi apparatus
E	0005795	cellular_component	Golgi stack
E	0006486	biological_process	obsolete protein glycosylation
E	0006493	biological_process	protein O-linked glycosylation
E	0016020	cellular_component	membrane
E	0016266	biological_process	protein O-linked glycosylation via N-acetyl-galactosamine
E	0016740	molecular_function	transferase activity
E	0016757	molecular_function	glycosyltransferase activity
E	0018243	biological_process	obsolete protein O-linked glycosylation via threonine
E	0030145	molecular_function	manganese ion binding
E	0030246	molecular_function	carbohydrate binding
E	0032580	cellular_component	Golgi cisterna membrane
E	0046872	molecular_function	metal ion binding
E	0048471	cellular_component	perinuclear region of cytoplasm
E	0051604	biological_process	protein maturation
F	0000139	cellular_component	Golgi membrane
F	0002639	biological_process	positive regulation of immunoglobulin production
F	0004653	molecular_function	polypeptide N-acetylgalactosaminyltransferase activity
F	0005515	molecular_function	protein binding
F	0005576	cellular_component	extracellular region
F	0005789	cellular_component	endoplasmic reticulum membrane
F	0005794	cellular_component	Golgi apparatus
F	0005795	cellular_component	Golgi stack
F	0006486	biological_process	obsolete protein glycosylation
F	0006493	biological_process	protein O-linked glycosylation
F	0016020	cellular_component	membrane
F	0016266	biological_process	protein O-linked glycosylation via N-acetyl-galactosamine
F	0016740	molecular_function	transferase activity
F	0016757	molecular_function	glycosyltransferase activity
F	0018243	biological_process	obsolete protein O-linked glycosylation via threonine
F	0030145	molecular_function	manganese ion binding
F	0030246	molecular_function	carbohydrate binding
F	0032580	cellular_component	Golgi cisterna membrane
F	0046872	molecular_function	metal ion binding
F	0048471	cellular_component	perinuclear region of cytoplasm
F	0051604	biological_process	protein maturation

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	615
Details	Domain: {"description":"Ricin B-type lectin","evidences":[{"source":"PROSITE-ProRule","id":"PRU00174","evidenceCode":"ECO:0000255"}]}

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site_id	SWS_FT_FI2
Number of Residues	630
Details	Region: {"description":"Catalytic subdomain A"}

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site_id	SWS_FT_FI3
Number of Residues	372
Details	Region: {"description":"Catalytic subdomain B"}

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site_id	SWS_FT_FI4
Number of Residues	42
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16434399","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24954443","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25939779","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2FFU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FFV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4D0T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4D11","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5AJP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FV9","evidenceCode":"ECO:0007744"}]}

Chain

Residue

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site_id	SWS_FT_FI5
Number of Residues	18
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16434399","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24954443","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25939779","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2FFU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FFV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4D0T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4D0Z","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4D11","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5AJP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FV9","evidenceCode":"ECO:0007744"}]}

Chain

Residue

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site_id	SWS_FT_FI6
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16434399","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24954443","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25939779","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2FFU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FFV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4D0T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4D0Z","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4D11","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5AJN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5AJO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5AJP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FV9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5NDF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6EGS","evidenceCode":"ECO:0007744"}]}

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site_id	SWS_FT_FI7
Number of Residues	6
Details	Site: {"description":"Not glycosylated"}

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site_id	SWS_FT_FI8
Number of Residues	6
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

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